Lorentz JÄNTSCHI (lori) works ?id=174
  • [id] => 174
  • [recorddate] => 2008:10:22:11:06:49
  • [lastupdate] => 2008:10:22:11:06:49
  • [type] => article
  • [place] => Albuquerque, NM
  • [subject] => informatics - applied; mathematics - statistics; medicine - informatics; research - evaluation; research - methodology
  • [relatedworks] => N/A
  • [file] => ?f=174
  • [mime] => application/pdf
  • [size] => 180843
  • [pubname] => Chemical Biology & Drug Design
  • [pubinfo] => Blackwell Publishing
  • [pubkey] => ISSN 1747-0277 eISSN 1747-0285
  • [workinfo] => 71(2): 173-179
  • [year] => 2008
  • [title] => A structural informatics study on collagen
  • [authors] => Lorentz JÄNTSCHI, Sorana D. BOLBOACĂ
  • [abstract] =>
    The work integrates of knowledge resulting from structure-activity relationships (SAR) analysis of amino acids with respect to characterization of 1 and 2 type I collagen chains. Specifically, fifteen amino acids and fourteen properties were investigated and their SAR models were obtained. The models were integrated into a web application and were used in order to predict the property of a set of six amino acids. The similarities in 1 and 2 type I collagen chains has been investigated starting from the observed and predicted properties of amino acids by using two-steps cluster analysis.
  • [keywords] => Amino Acid; Type I Collagen; Structure-Activity Relationship (SAR)
  • [acknowledgment] => The research was partly supported by the UEFISCSU Romania through research grants.