Lorentz JÄNTSCHI (lori) works ?id=174
- [id] => 174
- [recorddate] => 2008:10:22:11:06:49
- [lastupdate] => 2008:10:22:11:06:49
- [type] => article
- [place] => Albuquerque, NM
- [subject] => informatics - applied; mathematics - statistics; medicine - informatics; research - evaluation; research - methodology
- [relatedworks] => N/A
- [file] => ?f=174
- [mime] => application/pdf
- [size] => 180843
- [pubname] => Chemical Biology & Drug Design
- [pubinfo] => Blackwell Publishing
- [pubkey] => ISSN 1747-0277 eISSN 1747-0285
- [workinfo] => 71(2): 173-179
- [year] => 2008
- [title] => A structural informatics study on collagen
- [authors] => Lorentz JÄNTSCHI, Sorana D. BOLBOACĂ
- [abstract] =>
The work integrates of knowledge resulting from structure-activity relationships (SAR) analysis of amino acids with respect to characterization of 1 and 2 type I collagen chains. Specifically, fifteen amino acids and fourteen properties were investigated and their SAR models were obtained. The models were integrated into a web application and were used in order to predict the property of a set of six amino acids. The similarities in 1 and 2 type I collagen chains has been investigated starting from the observed and predicted properties of amino acids by using two-steps cluster analysis.
- [keywords] => Amino Acid; Type I Collagen; Structure-Activity Relationship (SAR)
- [acknowledgment] => The research was partly supported by the UEFISCSU Romania through research grants.