[id] => 174
[recorddate] => 2008:10:22:11:06:49
[lastupdate] => 2008:10:22:11:06:49
[type] => article
[place] => Albuquerque, NM
[subject] => informatics - applied; mathematics - statistics; medicine - informatics; research - evaluation; research - methodology
[relatedworks] => N/A
[file] => ?f=174
[mime] => application/pdf
[size] => 180843
[pubname] => Chemical Biology & Drug Design
[pubinfo] => Blackwell Publishing
[pubkey] => ISSN 1747-0277 eISSN 1747-0285
[workinfo] => 71(2): 173-179
[year] => 2008
[title] => A structural informatics study on collagen
[authors] => Lorentz JÄNTSCHI, Sorana D. BOLBOACĂ
[abstract] =>
The work integrates of knowledge resulting from structure-activity relationships (SAR) analysis of amino acids with respect to characterization of 1 and 2 type I collagen chains. Specifically, fifteen amino acids and fourteen properties were investigated and their SAR models were obtained. The models were integrated into a web application and were used in order to predict the property of a set of six amino acids. The similarities in 1 and 2 type I collagen chains has been investigated starting from the observed and predicted properties of amino acids by using two-steps cluster analysis.
[keywords] => Amino Acid; Type I Collagen; Structure-Activity Relationship (SAR)
[acknowledgment] => The research was partly supported by the UEFISCSU Romania through research grants.